There has been and continues to be a surge in biotech innovation. But a pertinent question arises: how frequently are older, now outdated technologies phased out? Precision's Ross Maclean, Phil Cyr and Ray Roth discuss the reluctance to abandon practices and technologies despite the availability of newer, better alternatives, and list how biopharma can lead the way.
Little attention is being focused on the impact the Inflation Reduction Act (IRA) may have on pharmaceutical R&D pipeline assets currently in Phase II or early Phase III of development. Precision's Kathy Lang and Ross Maclean outline challenges with assessing the true value of innovations that will have implications for IRA assessments, and propose suggestions around the importance of early planning to mitigate several elements of risk that manufacturers will face.
The presentation by Precision's Marlon Graf of a study with Jim Baumgardner, Iris Brewer, Jacquelyn Chou and Oliver Diaz and their colleagues was named an ISPOR 2023 Research Presentation Award Finalist. The Generalized Risk-Adjusted Cost-Effectiveness framework is a generalization of conventional cost-effectiveness analysis (CEA) and incorporates the effects of diminishing returns to health improvements as severity of illness increases. In the study presented by Marlon, the GRACE framework was applied to assess the comprehensive value of direct-acting antivirals (DAAs) for the treatment of hepatitis C (HCV) compared to peginterferon alfa and ribavirin (PEG/riba), accounting for differential valuations of life years versus quality of life, disease severity, insurance value, and other novel value elements. Please reach out to Marlon to learn more about the GRACE framework.
The presentation by Precision's Dylan Maciel of a study with Shannon Cope, Kevin Towle and Jeroen Jansen and their colleagues was named an ISPOR 2023 Research Presentation Award Finalist. Multi-level network meta-regression (ML-NMR) is a new method to perform network meta-analysis where for a subset of the studies we have individual participant data and for the remaining studies only aggregate level data from publications. In the study presented by Dylan, the feasibility of implementing ML-NMR for survival outcomes was evaluated. We learned a lot from this study that has direct benefit to future PRECISIONheor studies. Please contact Shannon Cope to learn more about ML-NMR (which is a method that is generalization of early work published by our Chief Scientist, Jeroen Jansen, in 2012).
The presentation by Precision's Laura Panattoni of a study with Tom Flottemesch, Natalie Land and Patrick Sullivan and their colleagues at ISPOR 2023 was named the Best General Podium Research Presentation. With this study, Laura and her colleagues aimed to quantify preferences for first line treatment attributes and treatment profiles among physicians who treat patients with aUC in 5 European countries (France, Germany, Italy, Spain, and the UK) with a DCE. Overall survival was the dominant attribute driving physicians’ choice of first line therapy, indicating that future therapies for aUC will need to provide substantial survival benefit to influence prescribing preferences. Reach out to Laura to learn more about this study.
The June Events Calendar is here! Stay up to date with all of the upcoming Precision conferences, on-demand events and recent thought leadership!
The MayEvents Calendar is here! Stay up to date with all of the upcoming Precision conferences, on-demand events and recent thought leadership!
The April Events Calendar is here! Stay up to date with all of the upcoming Precision conferences, on-demand events and recent thought leadership!
The March Events Calendar is here! Stay up to date with all of the upcoming Precision conferences, on-demand events and recent thought leadership!
New study demonstrates the feasibility of systematically integrating long-term survival estimates obtained from a formal expert elicitation study with empirical clinical trial data through a case study. Learn more about recent work of PRECISIONheor's Shannon Cope (co-primary author), Kevin Towle and Ali Mojebi and their co-authors.
The Precision Value & Health family of brands is now Precision AQ
Precision AQ helps life sciences companies navigate the complexities of commercialization across a product’s lifecycle. Our team is comprised of experts, advisors, and creators working to ensure patients have access to life-changing medicines.
Our global offerings include:
Our name, which stands for Precision Access Quotient, reflects our approach to removing barriers – fusing together science (IQ, or Intelligence Quotient) and empathy (EQ, or Emotional Quotient). The result is “AQ: Access Quotient”, a critical ingredient in navigating the therapy-to-patient journey informed by data-driven analytics and insights.
To find out more about our global services and our unified mission, empowering access to life-changing medicines for all, visit: Precision AQ
